Table 3: Statistical significant dates involving Hox polymorphisms.

Groups Polymorphism Nucleoside MBS patients (n = 30) Control groups (n = 30) p-value
MBS patients Versus Non-MBS patients A315T (Hoxb1) MBS patients (n = 30) Non-MBS patients (n = 30)
AA 26 (86.7) 17 (56.7) 0.02
AT 4 (13.3) 12 (40)
TT 0 (0) 1 (3.3)
MBS patients Versus Non-consanguineous and Non-syndromic patients (control group 2) C243T (Hoxb1) MBS patients (n = 30) Non-consanguineous and non- syndromic (n = 15) p-value
CC 22 (73.3) 6 (40) 0.03
CT 8 (26.7) 7 (46.7)
TT 0 (0) 2 (13.3)
A315T (Hoxb1) AA 26 (86.7) 7 (46.6) 0.01
AT 4 (13.3) 7 (46.7)
TT 0 (0) 1 (6.7)
G456A (Hoxb1) GG 20 (66.7) 5 (33.3) 0.02
GA 10 (33.3) 7 (46.7)
AA 0 (0) 3 (20)
MBS patients Versus Their relatives (Control group 1) G218A (Hoxa1) MBS patients (n = 30) Consanguineous (n = 15) p-value
GG 0 (0) 1 (6.6) 0.03
GA 11 (36.7) 1 (6.7)
AA 19 (63.3) 13 (86.7)