Mean values with standard (Std) error obtained by Aperio Technologies 2 (AT2) and data obtained by two photon excitation microscopy measures of total fibrosis percent (TFP), aggregated fiber percentage (AFP), total number of fibers (TNF) and number of fiber cross-links (FCL) with associated standard error for means, in relation to averaged and rounded histologic scores.

Table 1: Mean values with standard (Std) error obtained by Aperio Technologies 2 (AT2) and data obtained by two photon excitation microscopy measures of total fibrosis percent (TFP), aggregated fiber percentage (AFP), total number of fibers (TNF) and number of fiber cross-links (FCL) with associated standard error for means, in relation to averaged and rounded histologic scores.

	Score 0 (n = 7)		Score 1 (n = 6)		Score 2 (n = 15)		Score 3 (n = 11)		Score 4 (n = 10)
	Mean	Std. error	Mean	Std. error	Mean	Std. error	Mean	Std. error	Mean	Std. error	p value
TFP (%)	4.4	1.8	4.0	1.1	4.0	0.6	7.7	1.3	12.3	2.6	0.001
AFP (%)	3.1	1.5	2.6	0.8	2.6	0.5	5.6	1.0	8.5	1.9	0.003
TNF	233	14	233	33	278	28	316	21	535	86	0.000
FCL	7215	1265	5420	830	6786	815	9964	1809	18766	4655	0.003
AT2 (%)	3.2	0.5	3.3	0.7	4.9	0.7	7.7	1.2	21.2	2.8	0.000