Table 1: Results of serum, fecal, liver and colonic samples analysis from different experimental groups.

 

 

CN

CNDMH

CHOL

CHOLDMH

Initial weight (g)

180 ± 6

166 ± 7

147 ± 7

152 ± 3

Final weight (g)

314 ± 9

297 ± 16

291 ± 16

296 ± 7

Gain weight (g)

134 ± 7

149 ± 7

146 ± 8

144 ± 7

Triglycerides (mg/dl)

82 ± 4

59 ± 4*

85 ± 7

58 ± 5*

Total cholesterol (mg/dl)

128 ± 8

123 ± 8

111 ± 5

105 ± 7

HDL-cholesterol (mg/dl)

36 ± 3

37 ± 2

36 ± 2

34 ± 1

Hepatic cholesterol (mg/dl)

31 ± 2

37 ± 3

35 ± 3

33 ± 2

Fecal Cholesterol (mg/dl)

34 ± 5

24 ± 3

66 ± 3**

69 ± 5++

Bifidobacteria (UFC/g)

4.35 ± 3.39×1010

8.37 ± 3.10×1010

9.39 ± 3.64×1010

4.48 ± 2.81×1010

Fecal pH

7.0 ± 0.3

7.2 ± 0.3

6.5 ± 0.1

7.1 ± 0.3*

PCNA (%)

5.76 ± 0.91

16.20 ± 1.70

8.44 ± 0.23

20.48 ± 0.37++

ACF/field

0

0.68 ± 0.16

0

0.41 ± 0.50

(AC/ACF)

0

2.52 ± 0.33

0

2.11 ± 0.21

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Results are expressed as mean ± standard error. * p < 0.01, compared to the group treated with the respective diet without DMH; **compared to CN group; ++compared to CNDMH group. Standard diet (CN); standard diet + cholesterol 1% (CHOL); standard diet + DMH (CNDMH) and standard diet + cholesterol 1%+ DMH (CHOLDMH). PCNA (proliferating cell nuclear antigen), ACF (Aberrant crypt foci) and AC/ACF (aberrant crypt/aberrant crypt foci).