After IHC staining, pathologists revise their readings, most frequently from indeterminate to no LVSI. Each cell shows the median number of cases that received the row rating before IHC staining and the column rating after IHC staining, expressed as median ± interquartile range. (+) denotes LVSI positive. (-) LVSI negative. (?) LVSI indeterminate.

Table 3: After IHC staining, pathologists revise their readings, most frequently from indeterminate to no LVSI. Each cell shows the median number of cases that received the row rating before IHC staining and the column rating after IHC staining, expressed as median ± interquartile range. (+) denotes LVSI positive. (-) LVSI negative. (?) LVSI indeterminate.

		LVSI (+) IHC
		+	-	?
LVSI (-) IHC	+	6.5 ± 1.5	4.5 ± 0.5	0 ± 0.75
	-	1.5 ± 1.25	37 ± 5.875	1 ± 1.125
	?	1.5 ± 0.5	14.5 ± 6	0.5 ± 0.5