Parameters

Positive

Negative

Chi- square value

P-values

Cyclin D1

Cyclin D1

Age of patients (years)

30-39

0(0%)

 1(3.3%)

14.25

0.716

40-49

8 (26.6%)

 3(10%)

50-59

5 (16.6%)

 4(13.3%)

60-69

6(20%)

 1(3.3%)

≥ 70

1 (3.3%)

 0(0%)

SBR grade

I

0 (0%)

0 (0%)

01.296

0.255

II

14 (46.6%)

4(13.3%)

III

7(23.3%)

 5(16.6%)

Lymph node status

Negative

10 (33.3%)

2(6.6%)

13.7

0.089

Positive

11(36.6%)

7 (23.3%)

T stage/ Tumors size (cm)

< 2 cm

0 (0%)

5 (16.6%)

19.81

0.178

2 – 5 cm

13(43.3%)

2(6.6%)

> 5 cm

8(26.6%)

7(23.3%)

Estrogen receptor status

Negative

5(16.6%)

9 (30%)

14.6

0.001

Positive

16(53.3%)

0(0%)

Progesterone receptor status

Negative

5 (16.7%)

8 (26.6%)

10.86

0.002

Positive

16 (53.3%)

1 (3.3%)

Ki-67 proliferation marker status

Less than 10%

9(30%)

8 (26.6%)

5.4

0.020

More than 10%

12 (40%)

1(3.3%)

Molecular Classification

Luminal A

6(20%)

0 (0%)

14.762

  0.005

Luminal B

4 (13.3%)

1 (3.3%)

Triple Negative

4 (13.3%)

6 (20%)

Normal Like

7 (23.3%)

0 (0%)

Her2 neu enriched

0(0%)

2 (6.6%)

Metastasis

Bone

2 (6.6%)

 2 (6.6%)

0.780

0.377

Liver

2 (6.6%)

0 (0%)

0.361

0.548

Lung

0 (0%)

2 (6.6%)

2.30

0.129

Brain

3 (10%)

1 (3.3%)

0.74

0.709