Table 3: Early stage tumors vs. late-stage tumors (N = 73) QLQ C-30 & QLQH & N-35.

Scales (QLQ-C30)

Stage

student t Test

P value

I/II (n = 17)

III/IV (n = 56)

Global health status

61.76 ± 28.27

68.75 ± 22.2

0.2909

Physical functioning

89.8 ± 10.83

85.6 ± 16.52

0.3276

Role functioning

90.2 ± 16.73

87.5 ± 22.53

0.6499

Emotional functioning

81.37 ± 21.96

73.66 ± 24.91

0.2552

Cognitive functioning

85.29 ± 26.27

89.58 ± 18.14

0.447

Social functioning

78.43 ± 30.48

88.99 ± 20.91

0.1079

Fatigue

22.88 ± 15.45

29.96 ± 22.32

0.2264

Nausea and vomiting

2.941 ± 6.549

3.571 ± 9.382

0.7972

Pain

17.65 ± 27.93

17.56 ± 21.18

0.989

Dyspnoea

9.804 ± 19.6

1.19 ± 6.242

0.0053

Insomnia

17.65 ± 29.15

16.07 ± 22.91

0.8167

Appetite loss

25.49 ± 34.42

20.24 ± 29.6

0.5393

Constipation

25.49 ± 25.08

11.9 ± 20.53

0.0264

Diarrhoea

3.922 ± 11.07

4.167 ± 12.81

0.9435

Financial difficulties

58.82 ± 38.24

52.38 ± 35.31

0.5201

QLQ H&N-35

Pain

21.08 ± 28.73

16.82 ± 17.59

0.4580

Swallowing

19.61 ± 21.84

26.04 ± 20.72

0.2718

Senses problems

17.65 ± 21.63

19.35 ± 18.74

0.7532

Speech problems

26.8 ± 29.15

26.59 ± 21.37

0.9742

Trouble with social eating

34.8 ± 33.36

29.32 ± 26.92

0.4890

Trouble with social contact

26.27 ± 31.93

18.33 ± 21.32

0.2384

Less sexuality

15.69 ± 29.15

20.24 ± 30.77

0.5905

Teeth

33.33 ± 33.33

32.14 ± 29.79

0.8888

Opening mouth

45.1 ± 35.24

41.07 ± 37.6

0.6961

Dry mouth

37.25 ± 35.12

50.6 ± 33.63

0.1605

Sticky saliva

29.41 ± 35.12

30.95 ± 32.32

0.8665

Coughing

17.65 ± 20.81

14.88 ± 18.98

0.6084

Felt ill

23.53 ± 28.3

30.95 ± 29.72

0.3650

Pain killers

23.53 ± 43.72

21.43 ± 41.4

0.8570

Nutritional supplements

35.29 ± 49.26

21.43 ± 41.4

0.2514

Feeding tube

0 ± 0

1.786 ± 13.36

NA

Weight loss

41.18 ± 50.73

17.86 ± 38.65

0.0471

Weight gain

29.41 ± 46.97

55.36 ± 50.16

0.0623