Table 3: Early stage tumors vs. late-stage tumors (N = 73) QLQ C-30 & QLQH & N-35.
| 
 Scales (QLQ-C30)  | 
 Stage  | 
 student t Test P value  | 
|
| 
 I/II (n = 17)  | 
 III/IV (n = 56)  | 
||
| 
 Global health status  | 
 61.76 ± 28.27  | 
 68.75 ± 22.2  | 
 0.2909  | 
| 
 Physical functioning  | 
 89.8 ± 10.83  | 
 85.6 ± 16.52  | 
 0.3276  | 
| 
 Role functioning  | 
 90.2 ± 16.73  | 
 87.5 ± 22.53  | 
 0.6499  | 
| 
 Emotional functioning  | 
 81.37 ± 21.96  | 
 73.66 ± 24.91  | 
 0.2552  | 
| 
 Cognitive functioning  | 
 85.29 ± 26.27  | 
 89.58 ± 18.14  | 
 0.447  | 
| 
 Social functioning  | 
 78.43 ± 30.48  | 
 88.99 ± 20.91  | 
 0.1079  | 
| 
 Fatigue  | 
 22.88 ± 15.45  | 
 29.96 ± 22.32  | 
 0.2264  | 
| 
 Nausea and vomiting  | 
 2.941 ± 6.549  | 
 3.571 ± 9.382  | 
 0.7972  | 
| 
 Pain  | 
 17.65 ± 27.93  | 
 17.56 ± 21.18  | 
 0.989  | 
| 
 Dyspnoea  | 
 9.804 ± 19.6  | 
 1.19 ± 6.242  | 
 0.0053  | 
| 
 Insomnia  | 
 17.65 ± 29.15  | 
 16.07 ± 22.91  | 
 0.8167  | 
| 
 Appetite loss  | 
 25.49 ± 34.42  | 
 20.24 ± 29.6  | 
 0.5393  | 
| 
 Constipation  | 
 25.49 ± 25.08  | 
 11.9 ± 20.53  | 
 0.0264  | 
| 
 Diarrhoea  | 
 3.922 ± 11.07  | 
 4.167 ± 12.81  | 
 0.9435  | 
| 
 Financial difficulties  | 
 58.82 ± 38.24  | 
 52.38 ± 35.31  | 
 0.5201  | 
| 
 QLQ H&N-35  | 
|||
| 
 Pain  | 
 21.08 ± 28.73  | 
 16.82 ± 17.59  | 
 0.4580  | 
| 
 Swallowing  | 
 19.61 ± 21.84  | 
 26.04 ± 20.72  | 
 0.2718  | 
| 
 Senses problems  | 
 17.65 ± 21.63  | 
 19.35 ± 18.74  | 
 0.7532  | 
| 
 Speech problems  | 
 26.8 ± 29.15  | 
 26.59 ± 21.37  | 
 0.9742  | 
| 
 Trouble with social eating  | 
 34.8 ± 33.36  | 
 29.32 ± 26.92  | 
 0.4890  | 
| 
 Trouble with social contact  | 
 26.27 ± 31.93  | 
 18.33 ± 21.32  | 
 0.2384  | 
| 
 Less sexuality  | 
 15.69 ± 29.15  | 
 20.24 ± 30.77  | 
 0.5905  | 
| 
 Teeth  | 
 33.33 ± 33.33  | 
 32.14 ± 29.79  | 
 0.8888  | 
| 
 Opening mouth  | 
 45.1 ± 35.24  | 
 41.07 ± 37.6  | 
 0.6961  | 
| 
 Dry mouth  | 
 37.25 ± 35.12  | 
 50.6 ± 33.63  | 
 0.1605  | 
| 
 Sticky saliva  | 
 29.41 ± 35.12  | 
 30.95 ± 32.32  | 
 0.8665  | 
| 
 Coughing  | 
 17.65 ± 20.81  | 
 14.88 ± 18.98  | 
 0.6084  | 
| 
 Felt ill  | 
 23.53 ± 28.3  | 
 30.95 ± 29.72  | 
 0.3650  | 
| 
 Pain killers  | 
 23.53 ± 43.72  | 
 21.43 ± 41.4  | 
 0.8570  | 
| 
 Nutritional supplements  | 
 35.29 ± 49.26  | 
 21.43 ± 41.4  | 
 0.2514  | 
| 
 Feeding tube  | 
 0 ± 0  | 
 1.786 ± 13.36  | 
 NA  | 
| 
 Weight loss  | 
 41.18 ± 50.73  | 
 17.86 ± 38.65  | 
 0.0471  | 
| 
 Weight gain  | 
 29.41 ± 46.97  | 
 55.36 ± 50.16  | 
 0.0623  |