Table 8: Mean values ± standard deviation of osteocalcin levels in the gingival crevicular fluid (ng/ml) in Group I treated with standard scaling and root planning plus 20mg doxycycline twice/day for 3 months; group II treated with standard scaling and root planning plus 30mg CoQ10 twice/day for 3 months; group III treated with standard scaling and root planning plus 20mg doxycycline and 30mg CoQ10 twice/day for 3 months; group IV treated with standard scaling and root planning only. Letters a, b, and c refer to the degree of significance at *P<0.05; significant difference was found among groups marked by different letters (a,b,c) and no significant difference was found among groups marked by similar letters.

Time N Group I Group II Group III Group IV P value
Baseline 10 1.17 ± 0.06b 1.23 ± 0.07ab 1.27 ± 0.12a 1.147 ± 0.04b 0.03*
1 month 10 1.11 ± 0.08b 1.17 ±0.08ab 1.27 ± 0.23a 1.12 ± 0.06b 0.04*
3 months 10 1.1± 0.09b 1.17 ± 0.08ab 1.26 ± 0.20a 1.12 ± 0.06b 0.03*
P value 0.14 0.20 0.98 0.12