Expression of iron regulatory genes in lenses.

Table 6: Expression of iron regulatory genes in lenses.

	Expression of target genes (fold change to control, mean ± S.E. (p))
	Iron Uptake and Import			Iron Storage and Export			Iron homeostasis
Cataract type (n)	NIRE-DMT1	RE-DMT1	TFR2	FTH	FTL	FPN	IRP1	RP2	FBXL5
CC (34)	0.80 ± 0.14	1.99 ± 0.34	0.12 ± 0.02	0.12 ± 0.02	0.23 ± 0.04	0.21 ± 0.04	1.05 ± 0.18	1.83 ± 0.31	1.83 ± 0.31
CC (34)	(p=0.83)	(p=0.05)	(p=0.06)	(p=0.01)	(p=0.06)	(p=0.09)	(p=0.96)	(p=0.54)	(p=0.09)
NC (48)	0.59 ± 0.08	1.51 ± 0.11	0.40 ± 0.06	0.30 ± 0.09	0.53 ± 0.29	0.48 ± 0.09	1.69 ± 0.08	0.86 ± 0.04	0.25 ± 0.14
NC (48)	(p=0.61)	(p=0.58)	(p=0.35)	(p=0.14)	(p=0.41)	(p=0.31)	(p=0.60)	(p=0.87)	(p=0.07)
PSC (24)	0.06 ± 0.50	0.71 ± 0.07	0.07 ± 0.19	0.13 ± 0.27	0.46 ± 0.84	0.23 ± 0.27	4.86 ± 0.03	1.03 ± 0.00	0.07 ± 0.37
PSC (24)	(p=0.02)	(p=0.75)	(p=0.02)	(p=0.03)	(p=0.40)	(p=0.11)	(p=0.20)	(p=0.98)	(p=0.01)

CC: Cortical Cataract, NC: Nuclear Cataract, PSC: Posterior Subcapsular Cataract, N = Number of samples, p: p value.