Table 4: Spectral domain optical coherence tomography analysis of pigment epithelial detachment after switching to aflibercept in eyes with refractory neovascular age-related macular degeneration (n = 36).

 

Baseline median

(lower quartile, upper quartile)

12 weeks median

(lower quartile, upper quartile)

P value

48 weeks median

(lower quartile, upper quartile)

P value

PED Height

(Ķm)

209.5

(111.5, 325.8)

156

(103, 287)

P < 0.001

 

157

(85, 229.5)

P = 0.0002 Studentís t-test

P = 0.0002 Wilcoxon signed-rank test

PED Volume

(mm3)

0.905

(0.57, 2.13)

0.79

(0.46, 1.10)

P = 0.003 Studentís t-test

P = 0.002 Wilcoxon signed-rank test

0.67

(0.48, 1.08)

P = 0.005 Studentís t-test

P = 0.001 Wilcoxon signed-rank test