Cardiac Arrest

Neurogenic fever

COVID-19

Total patients

N = 39

N = 43

N = 10

Start temperature

< 35 °C

16 (41%)

0 (0%)

0 (0%)

35 °C - 37 °C

23 (59%)

18 (41.8%)

1 (10%)

37 °C - 39 °C

0 (0%)

22 (51.2%)

2 (20%)

> 39 °C

0 (0%)

3 (7%)

7 (70%)

Target temperature

33 °C

22 (56.4%)

0 (0%)

0 (0%)

36 °C

17 (43.6%)

22 (51.2%)

5 (50%)

37 °C

0 (0%)

21 (48.8%)

5 (50%)

Hypothermia treatment (induction & maintenance phases)

Hypothermia duration (h)

19.4 ± 9.4 h

18.5 ± 16.3 h

19.0 ± 12.3 h

Time from start to target^* (h)

2.8 ± 1.3 h

2.3 ± 0.8 h

3.1+ ± 1.6 h

Cooling rate (°C/h)

1.1 ± 0.4 °C/h

0.8 ± 0.3 °C/h

1.0 ± 0.4 °C

Fluctuations in maintenance

Variation at target (Mean ± SD °C)

0.4 ± 0.2 °C

0.4 ± 0.2 °C

0.3 ± 0.2 °C

% of time in target ± 0.5 °C

80.3 ± 25.3%

81.1 ± 20.0%

81.3 ± 29.0%

% of time 0.5-1.0 °C under target

4.6 ± 6.3%

4.8 ± 6.2%

3.2 ± 5.0%

% of time > 1.0 °C under target

1.0 ± 2.4%

2.3 ± 6.8%

0.2 ± 0.4%

% of time 0.5-1.0 °C above target

11.2 ± 16.0%

9.1 ± 13.2%

2.6 ± 3.7%

% of time > 1.0 °C above target

5.0 ± 10.7%

2.0 ± 4.9%

7.4 ± 15.8%

Lowest temperature (°C)

32.7 ± 2.2 °C

35.2 ± 1.5 °C

35.8 ± 2.5 °C

Normothermia treatment
(rewarm & maintenance phases)

Number of Rewarm/Maintenance phase

17/12

4/3

-

Normothermia duration (h)

12.3 ± 21.0h

0.6 ± 2.0h

-

Avg. Rewarming rate (°C/h)

0.2 ± 0.1°C/h

0.5 ± 0.2 °C/h

-

% of time rewarming rate > 0.5 °C/h

23.6 ± 22.7%

54.1 ± 29.3%

-