Table 5: Slopes and R2 values obtained from fitting the experimental in vitro dissolution data into the various release kinetic models.

Formulation Zero Order First order Higuchi [19] Hixson-Crowell Korsemeyer-Peppas [22]
Slope R2 Slope R2 Slope R2 Slope R2 Slope R2
NP1 -0.021 0.612 -0.004 0.933 8.665 0.933 0.022 0.821 0.7182 0.923
NP2 -0.087 0.652 -0.019 0.921 12.123 0.811 0.032 0.621 0.722 0.966
NP4 -0.127 0.369 -0.022 0.954 17.507 0.795 0.054 0.664 0.735 0.783