Table 5: Slopes and R2 values obtained from fitting the experimental in vitro dissolution data into the various release kinetic models.
Formulation | Zero Order | First order | Higuchi [19] | Hixson-Crowell | Korsemeyer-Peppas [22] | |||||
Slope | R2 | Slope | R2 | Slope | R2 | Slope | R2 | Slope | R2 | |
NP1 | -0.021 | 0.612 | -0.004 | 0.933 | 8.665 | 0.933 | 0.022 | 0.821 | 0.7182 | 0.923 |
NP2 | -0.087 | 0.652 | -0.019 | 0.921 | 12.123 | 0.811 | 0.032 | 0.621 | 0.722 | 0.966 |
NP4 | -0.127 | 0.369 | -0.022 | 0.954 | 17.507 | 0.795 | 0.054 | 0.664 | 0.735 | 0.783 |