Table 4: IC50 values of free MTX and MTX Loaded PLGA NPs in different concentrations after incubation time of 24 h, 48 h, 72 h and 168 h with U87MG cells.
Time incubation (h) | IC50 (µg/ml) free MTX | IC50 (µg/ml) MTX loaded PLGA nanoparticles |
---|---|---|
24 | 610.345 | 378.017 |
48 | 154.713 | 0.140 |
72 | 616.817 | 0.715 |