Inhibitory effect of total flavonoid extract of P. kotschyi on histamine-induced nitric oxide and hydrogen peroxide production by asthmatic patient neutrophil.

Table 3: Inhibitory effect of total flavonoid extract of P. kotschyi on histamine-induced nitric oxide and hydrogen peroxide production by asthmatic patient neutrophil.

Total flavonoid extract (µg.ml^-1)	NO production inhibition (%)	P value	H₂O₂production inhibition (%)	P value
8	13.26 ± 3.67	^**	11.21 ± 5.90	ns
16	39.48 ± 8.36	^***	35.12 ± 8.82	^***
32	51.88 ± 5.04	^***	62.91 ± 11.48	^***
64	69.01 ± 2.71	^***	85.65 ± 11.53	^***
128	98.52 ± 0.58	^***	97.30 ± 2.18	^***
IC₅₀	37.31 ± 4.11		32.05 ± 7.62

**p < 0.01, ***p < 0.001 compared with the effect of histamine (16 mM.l-1) which was 0% inhibition; Ns: No difference.