Table 1: Concentration-dependent inhibition percent of superoxide anion generation and neutrophil peroxidase (NPO) release of asthmatic patient neutrophil by total flavonoid extract of P. kotschyi.

Total flavonoid extract (µg.ml-1)

NPO release inhibition (%)

P value

Superoxide anion generation inhibition (%)

P value

8

5.89 ± 7.86

ns

2.62 ± 2.42

ns

16

18.28 ± 8.34

*

9.63 ± 3.50

ns

32

31.62 ± 6.87

***

19.70 ± 7.07

ns

64

54.53 ± 12.13

***

34.01 ± 20.44

**

128

72.29 ± 5.69

***

79.31 ± 8.62

***

IC50

76.03 ± 12.81

 

84.89 ± 11.95

 

*p < 0.05, **p < 0.01, ***p < 0.001 compared with effect of fMLP (10 mM.ml-1) which was 0% inhibition; Ns: No difference.