Table 2: Plasma levels of ASP and other parameters in 22 healthy controls and 25 patients with type 2 diabetes

Healthy controls Diabetes patients
Number of Samples [n] 22 25
Age [years old] 63±17 68±11
Body Mass Index (BMI) [kg/m2] 24.6±5.7 25.9±4.2
Hemoglobin A1c (NGSPb) [%] 5.2±0.7 6.6±0.8a
Immuno Reactive Insulin [μU/mL] 9.2±6.4 15.7±13.1
HOMA-IRc 2.7±1.0 6.5±7.4a
Adiponectin (ADN) [μg/mL] 8.7±1.8 4.1±3.6a
Tumor necrosis factor α (TNF α) [pg/mL] 0.9±0.8 3.1±5.9a
C3 [mg/dL] 92±22 121±37a
ic3b [μg/mL] 65±27 306±21a
Acylation stimulating protein (ASP) [μg/mL] 169±22 224±36a
Soluble membrane attack complex (sMAC) [ng/mL] 2.13±0.72 3.43±0.70a
Serum creatinine [mg/dL] 0.68±0.15 1.41±0.14a
Albumin creatinine ratio (ACR) [mg/gCr] 18±9 695±180a
eGFRd [mL/min] 78±32 50±25a


Values are expressed as mean±SD, a: statistically significant vs. healthy controls, b: National glycohemoglobin standardization program, c: homeostasis model assessment of insulin resistance, d: eGFR: estimated glomerular filtration rate.