Presence of cutaneous manifestations as predictive factor other clinical manifestations.

Table 3: Presence of cutaneous manifestations as predictive factor other clinical manifestations.

		With Cutaneous manifestations	Without Cutaneous manifestations	Univariable Analyses		Multivariable Analyses^*
		With Cutaneous manifestations	Without Cutaneous manifestations	OR (95% CI)	p value	OR (95% CI)	p Value
Clinical Manifestations, n (%)	Systemic	181 (44.2)	45 (54.2)	0.679 (0.423-1.091)	0.117
	Musculoskeletal	58 (42.0)	24 (49.0)	0.755 (0.393-1.453)	0.408
	Ocular	126 (10.7)	27 (13.5)	0.770 (0.493-1.203)	0.273
	Pleuropulmonary	133 (12.9)	35 (22.4)	0.490 (0.322-0.744)	0.002	0.519 (0.372-0.724)	0.001
	Cardiac	116 (10.3)	22 (13.0)	0.764 (0.471-1.248)	0.283
	Renal	299 (36.0)	46 (39.0)	0.880 (0.592-1.307)	0.540
	Neurological	277 (25.4)	41 (22.7)	1.161 (0.799-1.687)	0.460
	Hematologic	314 (52.0)	53 (70.7)	0.449 (0.267-0.758)	0.002	0.621 (0.440-0.876)	0.002

^*Variables included in step 1: gender, age at diagnosis and clinical manifestations.