Table 3: Frequency of each of the four FISH positive criteria in our 20 metastatic melanomas.
| Criteria for FISH Positivity | Number of Melanoma Cases Meeting Criteria/Total N (%) |
| Abnormal RREB1 % > 63 | 14/20 (70%) |
| Mean MYB signal # >2.5 | 1/20 (5%) |
| Mean CCND1 signal # > 2.5 | 5/20 (25%) |
| MYB loss (MYB < CEP6) % > 31 | 9/20 (45%) |