Table 3: Effect of CoQ10, NAC or their combination on serum total protein, albumin, creatinine and creatinine clearance.

Groups Total Protein (g/dL) Albumin (g/dL) Creatinine (mg/dL) Creatinine clearance (mL/min)
Control 7.55 ± 0.071 3.65 ± 0.042 0.426 ± 0.032 1.134 ± 0.088
STZ DN 4.83 ± 0.152a 1.55 ± 0.154a 2.96 ± 0.091a 0.238 ± 0.017ab
CoQ10 (10 mg/kg) 6.25 ± 0.152ab 2.46 ± 0.055ab 1.002 ± 0.050ab 0.615 ± 0.038ab
NAC (300 mg/kg) 6.13 ± 0.269ab 2.61 ± 0.094ab 1.06 ± 0.046ab 0.564 ± 0.052ab
CoQ10 + NAC 6.78 ± 0.119abd 2.96 ± 0.071abd 0.78 ± 0.036abcd 0.869 ± 0.083abcd

Values are expressed as mean ± SEM; n = 6; a: P < 0.001 as compared to normal control group; b: P < 0.001 as compared to diabetic control group; c: P < 0.001 as compared to diabetic CoQ10 alone treated group; d: P < 0.001 as compared to diabetic NAC alone treated group.