Table 1: Effect of coenzyme Q10, NAC or combination of both on body weight and kidney to body weight ratio (mg/g).
Groups | Body weight | Kidney to Body Weight Ratio (mg/g) | |
Initial at Week 0 | Final at Week 12 | ||
Control | 242.3 ± 0.919 | 351.7 ± 2.093* | 3.807 ± 0.041 |
STZ DN | 247.2 ± 1.796 | 210.7 ± 2.906a* | 10.45 ± 0.069a |
CoQ10 (10 mg/kg) | 249.0 ± 1.125 | 231.8 ± 0.749ab* | 6.800 ± 0.131ab |
NAC (300 mg/kg) | 249.0 ± 1.751 | 227.0 ± 1.983ab* | 7.098 ± 0.202ab |
CoQ10 + NAC | 246.2 ± 1.905 | 251.8 ± 1.642abcd* | 6.025 ± 0.174abcd |
Values are expressed as mean ± SEM; n = 6; a: P < 0.001 as compared to normal control group; b: P < 0.001 as compared to diabetic control group; c: P < 0.001 as compared to diabetic CoQ10 alone treated group; d: P < 0.001 as compared to diabetic NAC alone treated group; *P < 0.05 compared with the same group at 0 week.