Table 5: Effect of ARBs and antidiabetic agents on liver functions during 3 consecutive follow up.

Parameter ALT U/L AST U/L Albumin G/DL
Antihypertensive agents Antidiabetic agents 1st 2nd 3rd 1st 2nd 3rd 1st 2nd 3rd
ARBs Insulin 42.9 ± 10.2 37.7b ± 10.1 49.3 ± 14.4 30.4 ± 8.2 28.8 ± 7.2 36 ± 10.3 3.5b ± 0.2 3.4b ± 0.1 3.3b ± 0.2
Biguanide 57.8 ± 11.8 51.1 ± 13.3 71.3 ± 16.4 47.7 ± 11.8 35.2 ± 10.1 41.1 ± 11.5 3.5b ± 0.2 3.4 ± 0.0 3.5 ± 0.0
Biguanide + DPP-4 53.6 ± 14 72.1a ± 14.1 72.1 ± 15.2 44 ± 13 40.5 ± 10.9 45.1 ± 11.8 4.1a ± 0.1 3.8a ± 0.1 3.8a ± 0.1

Values represent mean ± SE.
Small alphabetical letter in the same column within the same parameters are significantly different between groups at P < 0.05 (Two way ANOVA).