Table 1: Effect of ACE inhibitors and antidiabetic agents on lipid profile during 3 consecutive follow ups.
Parameters | TC (mg/dl) | TG (mg/dl) | LDL (mg/dl) | HDL (mg/dl) | |||||||||
Antihypertensive agents | Antidiabetic agents | 1st | 2nd | 3rd | 1st | 2nd | 3rd | 1st | 2nd | 3rd | 1st | 2nd | 3rd |
ACEI | Insulin | 165.3 ± 11.6 | 157.2a ± 7.9 | 158.3 ± 8.9 | 123 ± 14.1 | 151 ± 24.2 | 117.6 ± 11.4 | 103 ± 9.5 | 96.5b ± 6.9 | 130.0 ± 36 | 44.0 ± 2.3 | 40.3 ± 2 | 40.3 ± 4.3 |
Biguanide | 193.3 ± 19.2 | 208.8b ± 20.2 | 186.7 ± 14.6 | 173.4 ± 30.2 | 147.3 ± 8.1 | 137.3 ± 7.9 | 118.3 ± 19.5 | 141.4a ± 21.6 | 130.5 ± 16.2 | 39.7 ± 1.7 | 39.7 ± 2.2 | 39.0 ± 0.8 | |
Biguanide + DPP-4I | 172 ± 7.9 | 176.4 ± 9.2 | 162.1 ± 9.5 | 137.8 ± 21.7 | 162.5 ± 6.6 | 144 ± 15.1 | 103.1 ± 9.7 | 104.3b ± 6.9 | 100 ± 4.2 | 39.7 ± 1.9 | 36.8 ± 3.4 | 37.6 ± 2.9 |
Values represent mean ± SE.
Different Small alphabetical letter in the same column within the same parameters are significant at P < 0.05 (Two way ANOVA).