Effect of IRC on Fasting Blood Glucose Level in Diabetic Rats after Single Oral Dose Administration.

Table 1: Effect of IRC on Fasting Blood Glucose Level in Diabetic Rats after Single Oral Dose Administration.

Group	Dose Mg/kg	Before Alloxan	After Alloxan (0 hr)	Blood glucose (mg/dl) at different time intervals (hrs)
Group	Dose Mg/kg	Before Alloxan	After Alloxan (0 hr)	2 hrs	4 hrs	6 hrs	8 hrs	24 hrs	ANOVA
I-Diabetic Control	-	96.67 ± 2.61	394.0 ± 25.5	426.7 ± 25.5	422.3 ± 26.7	396.5 ± 16.4	372.2 ± 7.3	370.2 ± 7.3	0.1342
II-Diabetic + IRC	50	96.83 ± 2.51	338.8 ± 2.97	379.2 ± 54.04	378.8 ± 3.49	363.7 ± 4.7	341.0 ± 8.8	358.5 ± 8.0	0.3799
III-Diabetic + IRC	500	93.00 ± 2.05	322.2 ± 2.27	375.5 ± 4.80	367.0 ± 7.26	347.2 ± 12.3	335.2 ± 11.43	350.5 ± 5.9	0.0003
IV-Diabetic + IRC	1000	92.33 ± 1.87	349.0 ± 9.94	365.5 ± 11.2	361.5 ± 7.94	339.0 ± 12.2	338.0 ± 12.2	328.3 ± 12.2	0.0401
V-Diabetic + IRC	2000	86.67 ± 1.17	331.70 ± 7.36	345.50 ± 5.34	348.30 ± 7.94	331.00 ± 7.94	323.70 ± 7.68	320.20 ± 6.09	0.0248
Dose Depend Effect				0.0032	0.0077	0.0044	0.0214	0.0018
VI-Diabetic + glibencla	5	92.83 ± 5.64	283.5 ± 12.78	234.7 ± 10.82	196.8 ± 7.60	188.5 ± 9.24	186.8 ± 6.61	188.5 ± 29.72	< 0.0001

Each value represent mean ± SEM (n = 6 rats per group).

0 hr = 48 hours after alloxan.