Table
3: Logistic
regression modeling to predict odds of poor glycemic control.
|
|
Univariate analysis |
Multivariate analysis |
||
|
Unadjusted
OR (95% CI) |
p
Value |
Adjusted
OR (95% CI) |
p
Value |
|
|
Quintile
of HbA1c variability |
|
|
|
|
|
1st |
Reference |
|
Reference |
|
|
2nd |
1.26
(0.93-1.71) |
0.3716 |
1.16
(0.85-1.59) |
0.3674 |
|
3rd |
1.39
(1.04-1.87) |
0.0574 |
1.05
(0.77-1.42) |
0.8548 |
|
4th |
1.78
(1.34-2.38) |
<
0.0001 |
1.14
(0.84-1.56) |
0.3872 |
|
5th |
2.52
(1.91-3.34) |
<
0.0001 |
0.98
(0.69-1.38) |
0.3335 |
|
Absolute
change in HbA1c |
1.09
(0.98-1.22) |
0.1021 |
1.14
(1.03-1.26) |
0.011 |
|
Mean
HbA1c |
1.70
(1.54-1.81) |
<
0.0001 |
1.70
(1.52-1.90) |
<
0.0001 |
|
Age
group (years) |
|
|
|
|
|
65-74 |
Reference |
|
Reference |
|
|
75-84 |
0.78
(0.65-0.95) |
0.136 |
0.86
(0.70-1.05) |
0.2073 |
|
≥
85 |
0.81
(0.62-1.06) |
0.4653 |
0.93
(0.70-1.24) |
0.6758 |
|
Gender |
|
|
|
|
|
Female |
Reference |
|
Reference |
|
|
Male |
1.06
(0.89-1.26) |
0.5079 |
1.08
(0.89-1.30) |
0.4542 |
|
Obesity |
1.18
(0.93-1.49) |
0.1686 |
1.07
(0.83-1.77) |
0.6078 |
|
Depression |
1.24
(0.89-1.72) |
0.1963 |
1.04
(0.67-1.60) |
0.8486 |
|
Chronic
kidney disease |
1.24
(1.01-1.53) |
0.0439 |
1.42
(1.08-1.86) |
0.0113 |
|
Modified
Charlson comorbidity index |
|
|
|
|
|
0 |
Reference |
|
Reference |
|
|
1-2 |
0.98
(0.79-1.23) |
0.8795 |
0.98
(0.77-1.25) |
0.3894 |
|
≥
3 |
1.01
(0.81-1.25) |
0.9068 |
0.88
(0.67-1.16) |
0.2147 |
|
DxCG
risk score tertile |
|
|
|
|
|
1st
(0.066 – 3.312) |
Reference |
|
Reference |
|
|
2nd
(3.313-7.911) |
0.91
(0.73-1.13) |
0.1439 |
0.90
(0.71-1.15) |
0.2272 |
|
3rd
(7.911-178.784) |
1.09
(0.89-1.35) |
0.1429 |
1.07
(0.77-1.49) |
0.3885 |
|
Emergency
department visit |
1.23
(1.02-1.48) |
0.0293 |
1.28
(0.99-1.64) |
0.0573 |
|
Number
of outpatient visit |
1.01
(0.99-1.03) |
0.2461 |
1.02
(0.99-1.05) |
0.1492 |
|
Any
hospitalization |
1.15
(0.92-1.44) |
0.2067 |
0.98
(0.73-1.31) |
0.8853 |
|
Number
of PCP/internist visit |
0.99
(0.98-1.01) |
0.648 |
0.98
(0.97-0.99) |
0.0171 |
|
Number
of specialist visit |
1.01
(0.99-1.02) |
0.3181 |
1.02
(1.00-1.04) |
0.0473 |
|
Number
of distinct generic drug |
1.02
(1.00-1.03) |
0.0479 |
0.99
(0.97-1.01) |
0.3899 |
|
Insulin
use |
1.20
(1.64-2.43) |
<
0.0001 |
1.36
(1.05-1.78) |
0.0226 |
*OR: odds ratio; CI: confidence
interval