Histological parameters evaluated in the pancreas of normoglycemic or diabetic rats treated for 7 days with vehicle or B. forficata extract

Table 4: Histological parameters evaluated in the pancreas of normoglycemic or diabetic rats treated for 7 days with vehicle or B. forficata extract (300 mg kg^-1).

Parameter	Animal Groups
Parameter	N Vehicle	N BFEE	D Vehicle	D BFEE
Presence of vacuoles	0	1	2	2
Apoptosis	0	0	0	1
Presence of MMN	0	0	1	1
Presence of nucleolus	0	0	2	1
Organization islets	0	0	2	1
Langerhans islets	3.7 ± 0.48	3.3 ± 0.58	1.8 ± 0.20^***	1.8 ± 0.81^***

Comparisons performed by one way ANOVA and Bonferroni. Legend: 0, no changes; 1, slight alterations; 2, moderate changes; MMN, Monomorphonuclear; N = normoglycemic; D = diabetic; BFEE = B. forficata ethanolic extract. Symbol: ^***p < 0.001 compared with the N vehicle by ANOVA and Bonferroni. Counted islets were carried out in 4 fields at 100x magnification at optical microscopy.