Table 2: Primary and secondary outcomes: adjusted regression coefficient or odds
ratio for electronic insulin protocol group to historical control group to
historical control group.
Outcome |
Control
group (N
= 87) |
Study
group (N = 136) |
Adjusteda regression coefficient or odds
ratio (95% Cl) |
p |
|
Mean
blood glucose during the first 120 hours |
|
|
|
|
|
Mean
blood glucose (mmol/L) |
8.7 |
8.65 |
-0.08
(-0.61, 0.46)b |
0.776 |
|
Glycemic
range during the first 120 hours |
|
|
|
|
|
Hyperglycemic
range ( > 10.0 mmol/L) |
311
(-28.4%) |
572
(-25.8%) |
-2.85
(-9.79, 4.09)b |
0.419 |
|
Hypoglycemic
range ( < 4.0 mmol/L |
16
(1.5%) |
28
(1.26%) |
-0.75
(-1.74, 0.24)b |
0.138 |
|
Glucose
variability during the first 120 hours |
|
|
|
|
|
Variability
during the first 120 hours |
8.75 |
6.38 |
-2.63
(-4.93, -0.33)b |
0.025 |
|
Hypoglycemia
during the first 120 hours |
|
|
|
|
|
Hypoglycemia
( < 2.9 mmol/L) during the first 120 hours |
16
(1.5%) |
28
(1.26) |
0.42
(0.14, 1.25)c |
0.12 |
|
Hospital
outcomes |
|
|
|
|
|
Ward
length of stay (days) |
9.6 |
11.1 |
0.26
(-2.32, 2.84)b |
0.842 |
|
In-hospital
mortality |
9 |
4 |
0.14
(0.03, 0.64)c |
0.011 |
|
Transfer
to ICU |
7 |
2 |
0.13
(0.02, 0.85)c |
0.034 |
aAdjusted for age, diabetes type, main hospital diagnosis (LRTI or
acute cardiac condition), and chronic therapy at admission (metformin, insulin)b
Adjusted regression coefficientc Adjusted
regression coefficient