Table 2: Time courses of changes in the clinical parameters in
the basal insulin group (A) and in the premixed insulin group (B).
(A)
|
|
0
w （n = 22） |
16
w （n = 22） |
P value |
|
Body weight (kg) |
60.4 ±
12.1 |
59.7 ±
12.1 |
0.006 |
|
Body mass index (kg/m2) |
23.2 ± 3.6 |
22.9 ± 3.7 |
0.005 |
|
HbA1c (%) |
7.87 ±
0.99 |
7.65 ±
0.76 |
0.246 |
|
Insulin dose (U/day) |
19.6 ± 9.8 |
19.5 ±
10.7 |
0.884 |
|
Systolic clinic blood pressure (mmHg) |
134.2 ± 16.1 |
127.3±
13.2 |
0.157 |
|
Diastolic clinic
blood pressure (mmHg) |
75.0 ± 10.3 |
69.4 ±
10.4 |
0.008 |
|
Total cholesterol (mg/dL) |
190.0 ± 49.9 |
178.6 ±
36.4 |
0.065 |
|
Triglyceride (mg/dL) |
135.5 ± 84.7 |
144.0 ±
106.2 |
0.530 |
|
High-density lipoprotein cholesterol
(mg/dL) |
59.4 ± 21.3 |
55.0 ±
14.6 |
0.060 |
|
Low-density lipoprotein
cholesterol (mg/dL) |
103.5 ± 41.1 |
94.8 ±
32.9 |
0.098 |
Values
are expressed as means ± S.D.
(B)
|
|
0
w（n = 21） |
16 w（n
= 21） |
P value |
|
Body weight （kg） |
56.7 ± 9.8 |
57.1 ± 9.8 |
0.329 |
|
Body mass index （kg/m2） |
23.3 ± 3.0 |
23.4 ± 2.9 |
0.288 |
|
HbA1c (%) |
7.96 ±
1.17 |
7.36 ± 1.35 |
0.002 |
|
Insulin dose (U/day) |
23.5 ± 9.0 |
23.1 ± 8.3 |
0.490 |
|
Systolic clinic
blood pressure (mmHg) |
135.7 ±
20.1 |
130.2 ± 14.9 |
0.260 |
|
Diastolic clinic
blood pressure (mmHg) |
71.1 ±
11.3 |
65.7± 10.8 |
0.013 |
|
Total
cholesterol (mg/dL) |
188.0 ±
43.5 |
174.0 ± 35.8 |
0.082 |
|
Triglyceride (mg/dL) |
124.5 ±
69.7 |
117.8 ± 46.9 |
0.563 |
|
High-density
lipoprotein cholesterol (mg/dL) |
55.3 ±
12.3 |
52.6 ± 12.3 |
0.053 |
|
Low-density lipoprotein cholesterol (mg/dL) |
107.7 ±
33.9 |
97.9 ± 25.4 |
0.155 |
Values are
expressed as means ± S.D.