Table 1: Rats aged 16 weeks at sacrifice - Treatment by subcutanous injections
Total weight and weight of selected organs of 16 weeks old Wistar rats, treated for six weeks with daily subcutaneous injection of 150 mg/kg/day metformin (Metformin) or saline (Controls). All values are presented as median and [range]. Range indicates the lowest and the highest value observed. P-values < 0.05 were considered statistically significant.

Metformin Controls p-value
Total weight, aged 10 weeks (g) 327 [292-348] 329 [305-341] 0.69
Total weight at sacrifice, aged 16 weeks (g) 380 [306-414] 406 [338-438] 0.047
Kidney (g) 1.60 [1.48-1.68] 1.72 [1.49-2.08] 0.09
Liver (g) 13.23 [11.03-14.73] 12.42 [9.98-14.05] 0.16
Heart (g) 1.7 [1.42-1.83] 1.63 [1.47-1.72] 0.62