Table 9: GRADE table of evidence (created using https://www.GradePro.com).
Certainty assessment |
№ of patients |
Effect |
Certainty |
Importance |
||||||||
№ of studies |
Study design |
Risk of bias |
Inconsistency |
Indirectness |
Imprecision |
Other consideration |
metronomic chemotherapy |
without metronomic chemotherapy |
Relative |
Absolute |
||
Overall response rate (assessed with RECIST guidelines version 1.1) |
||||||||||||
2 |
randomised trials |
serious |
not serious |
not serious |
not serious |
None |
44/71 (62.0%) |
32/67 (47.8%) |
RR 1.29 |
139 more per 1,000 |
⨁⨁⨁◯ |
IMPORTANT |
CI: Confidence Interval; RR: Risk Ratio