Table 3: Predicting sensitivity of CMS classification and IPS for disease control rate of anti-EGFR treatment in GSE104645.

 

Cases with wild type RAS n = 91

Cases with wild type RAS n = 91

Cases with CMS1/3/4

n = 54

Cases with CMS2

n = 37

 

CMS1/3/4

CMS2

Low IPS

High IPS

Low IPS

High IPS

Low IPS

High IPS

PD

20 (37.0)

3 (8.1)

18 (38.3)

5 (11.4)

17 (48.6)

3 (15.8)

1 (8.3)

2 (8.0)

DC

34 (63.0)

34 (91.9)

29 (61.7)

39 (88.6)

18 (51.4)

16 (84.2)

11 (91.7)

23 (92.0)

χ2/P

9.729/0.002

8.729/0.003

5.675/0.017

1.000

Fisher’s exact probability