Table 3: Predicting sensitivity of CMS classification and IPS for disease control rate of anti-EGFR treatment in GSE104645.
Cases with wild type RAS n = 91 |
Cases with wild type RAS n = 91 |
Cases with CMS1/3/4 n = 54 |
Cases with CMS2 n = 37 |
|||||
CMS1/3/4 |
CMS2 |
Low IPS |
High IPS |
Low IPS |
High IPS |
Low IPS |
High IPS |
|
PD |
20 (37.0) |
3 (8.1) |
18 (38.3) |
5 (11.4) |
17 (48.6) |
3 (15.8) |
1 (8.3) |
2 (8.0) |
DC |
34 (63.0) |
34 (91.9) |
29 (61.7) |
39 (88.6) |
18 (51.4) |
16 (84.2) |
11 (91.7) |
23 (92.0) |
χ2/P |
9.729/0.002 |
8.729/0.003 |
5.675/0.017 |
1.000† |
†Fisher’s exact probability