Table 1: MiR-497-5p levels in mesothelioma tissues, plasma and prognostic factors.

Parameter

n

MiR-497-5P in tissues

P

MiR-497-5P in plasma

P

 

Mean

SD

 

Mean

SD

 

 

Gender

< 0.0001*

 

 

0.0061*

Male

Female

13

17

0.460

2.156

0.240

0.936

1.944

2.627

0.558

0.671

 

Performance Status

< 0.0001*

 

 

< 0.0001*

0-1

2

22

8

1.324

0.482

0.391

0.181

1.248

0.353

0.451

0.146

 

Pathology

< 0.0001*

 

 

< 0.0001*

Epithelioid

Non-epithelioid

20

10

1.393

0.512

0.337

0.171

1.307

0.313

0.493

0.157

 

LDH level

< 0.0001

 

 

 

Normal

high

17

13

1.452

0.638

0.256

0.372

1.361

0.611

0.246

0.341

 

< 0.0001*

Platelet Count

< 0.0001*

 

 

< 0.0001*

Normal

high

17

13

1.452

0.638

0.256

0.372

1.361

0.611

0.246

0.341

 

WBCs

0.0003*

 

 

0.0005*

Normal

High

14

16

1.430

0.810

0.277

0.498

1.333

0.775

0.263

0.468

 

Hemoglobin %

< 0.0001*

 

 

< 0.0001*

≤ 14 gm/dl

> 14 gm/dl

12

18

0.258

1.469

0.546

0.173

0.527

1.375

0.165

0.246

 

T

0.0010**

 

 

0.0015**

T1

T2

T3

11

15

4

1.364

1.106

0.348

0.268

0.519

0.148

1.264

1.052

0.347

0.247

0.490

0.137

 

N

< 0.0001*

 

 

< 0.0001*

N0

N1

21

9

0.002

0.501

0.370

0.177

1.275

0.339

0.477

0.158

 

Stage

 

 

 

 

I

II

21

9

1.36

0.37

0.501

0.177

< 0.0001*

1.275

0.339

0.477

0.158

 

< 0.0001*

Type of Surgery

 

 

 

 

0.0015**

Complete Resection

Partial Resection

Un resectable

11

15

4

1.364

1.106

0.348

0.268

0.520

0.148

0.001**

1.264

1.052

0.347

0.247

0.490

0.137