Table 2: Risk of breast cancer in female Hodgkin's patients and their relatives, 1966-20141
|Comparison||Breast Cancer HR||95% CI||P|
|Baseline BC risk in FDR of BC patients in Utah||1.8||(1.7-1.8)||< 0.0001|
|Risk in HL patients vs. controls|
|BC risk in HL patients when BC in FDR||3.8||(1.9-7.7)||0.0003|
|BC risk in HL patients when no BC in FDR||1.7||(1.2-2.5)||0.002|
|Risk in HL patients only|
|HL with BC in FDR vs. HL with no BC in FDR||3.3||(1.6-7.1)||0.002|
|HL with BC in FDR vs. HL with no BC in FDR, for HL diagnosed 1966-1999||3.7||(1.7-7.9)||< 0.001|
|Risk in FDR of HL vs. FDR of controls:|
|FDR of HL patients with BC||2.8||(1.4-5.6)||0.005|
|FDR of HL diagnosed 1966-1999 with BC||2.9||(1.4-5.9)||0.003|
|FDR of HL patients with no BC||1||(0.8-1.4)||0.97|
|FDR of HL diagnosed 1966-1999 with no BC||0.9||(0.6 - 1.2)||0.38|
1Adjusted for race/ethnicity and age.
FDR: First-Degree Relative; HL: Hodgkin's Lymphoma; BC: Breast Cancer.