Table 7: Adverse events.

Grade 1 Grade 2 Grade 3 Grade 4 Grade 3/4 (%)
Thrombocytopenia 24 11 11 2 21%
Increased ALT and/or AST 28 11 3 0 5%
Hemorrhage 8 1 0 0 0
Fatigue 17 7 0 0 0
Rash 3 0 1 0 2%
Peripheral sensory neuropathy 3 2 0 0 0
Neutropenia 0 0 1 0 2%
Nausea 6 4 0 0 0
Patients with dose delays because of side effects, N (%) 5 (8%)
Patients with dose reductions because of side effects, N (%) 11 (17%)
Ended therapy because of side effects, N (%) 5 (8%)

ALT: alanine aminotransferase; AST: aspartate aminotransferase; N: number of patients.