Table 2: Absorbing events crude cumulative incidence regression model based on pseudo-values. For each covariate the exponent of regression coefficient is the estimate of the ratio between crude cumulative incidences. N0 and N1 indicates absence or presence of axillary lymph node metastases respectively. T is pathological tumour size (in cm). PgR +,- indicates > 25 or <= 25 femtomoles progesterone receptors per milligram of cytosolic protein respectively, ER +,- indicates >10 fmoli or <= 10 of estrogen receptors femtomoles per milligram of cytosolic protein respectively time and time’ are the spline bases for time.

Estimate

Standard Error

Wald statistic

p-value

(Intercept)

-4.954

0.666

55.281

< 0.001

time

0.02

0.004

26.545

< 0.001

time'

-0.009

0.005

3.023

0.082

PGR (+ vs. -)

-0.366

0.337

1.181

0.277

ER (+ vs. -)

-0.488

0.408

1.426

0.232

T (1-2 vs. ≤ 1)

-0.274

0.393

0.489

0.484

T (> 2 vs. ≤ 1)

-0.469

0.55

0.725

0.394

N (1 vs. 0)

-0.139

0.36

0.149

0.699

age (51-60 vs. ≤50)

0.658

0.427

2.373

0.123

age (> 60 vs. ≤ 50)

1.576

0.427

13.597

< 0.001