GSTP1 methylation status

All breast cancer cases

Methylated breast tumor

Unmethylated breast tumor

Recreational physical activity (RPA)a

ER+PR+/
ER-PR-

ORd

95% CIe

 

ER+PR+/                                    ER-PR-

OR

95% CI

 

ER+PR+/
ER-PR-

OR

95% CI

p for interaction

Inactive

55/18

1.00

reference

12/6

1.00

reference

43/12

1.00

reference

0.068

Low RPAd (≤ 9.23 hrs/wk)

67/27

0.84

(0.42, 1.68)

16/3

not estimated

51/24

0.60

(0.27, 1.34)

High RPA (>9.23 hrs/wk)

69/18

1.28

(0.61, 2.69)

18/5

1.85

(0.46, 7.48)

51/13

1.11

(0.46, 2.68)

a Low RPA ≤ 9.23 hours/week, High RPA > 9.23 hours/week

 

Supplemental Table 2: Age-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between postmenopausal recreational physical activity (RPA) and ER+PR+ breast cancer (vs. ER-PR- breast cancer) considering the GSTP1 methylation status of the tumor (methylated vs. unmethylated), the Long Island Breast Cancer Study Project (1996-1997).