GSTP1
methylation status |
||||||||||||
All
breast cancer cases |
Methylated
breast tumor |
Unmethylated
breast tumor |
||||||||||
Recreational
physical activity (RPA)a |
ER+PR+/ |
ORd |
95% CIe |
|
ER+PR+/ ER-PR- |
OR |
95% CI |
|
ER+PR+/ |
OR |
95% CI |
p for
interaction |
Inactive |
55/18 |
1.00 |
reference |
12/6 |
1.00 |
reference |
43/12 |
1.00 |
reference |
0.068 |
||
Low RPAd
(≤ 9.23 hrs/wk) |
67/27 |
0.84 |
(0.42, 1.68) |
16/3 |
not estimated |
51/24 |
0.60 |
(0.27, 1.34) |
||||
High RPA (>9.23 hrs/wk) |
69/18 |
1.28 |
(0.61, 2.69) |
18/5 |
1.85 |
(0.46, 7.48) |
51/13 |
1.11 |
(0.46, 2.68) |
|||
a Low RPA ≤ 9.23 hours/week, High RPA > 9.23
hours/week |
Supplemental Table 2: Age-adjusted odds ratios (ORs) and 95% confidence intervals
(CIs) for the associations between postmenopausal recreational physical
activity (RPA) and ER+PR+ breast cancer (vs. ER-PR- breast cancer) considering
the GSTP1 methylation status of the tumor (methylated vs. unmethylated),
the Long Island Breast Cancer Study Project (1996-1997).