Table 2: Profiles and
clinical outcomes of patients who completed the regimen
Clinical Background |
Immunological Response |
Antitumor Response |
||||||||
Dose |
Age |
Gender |
Origin |
Status |
HLA class I |
Tetramer |
ELISPOT |
RECIST |
CEA |
CA19-9 |
0.3
mg |
63 |
Woman |
Pancreas |
Inoperable |
+ |
35 |
-17 |
SD |
Decreased |
Decreased |
0.3
mg |
69 |
Woman |
Pancreas |
Inoperable |
+ |
5 |
-31 |
SD |
WNL |
Increased |
0.3
mg |
53 |
Woman |
Pancreas |
Post-op |
- |
7 |
6 |
PD |
Increased |
Increased |
0.3
mg |
68 |
Man |
Pancreas |
Post-op |
+ |
+ |
17 |
PD |
Increased |
Increased |
0.3
mg |
78 |
Man |
Man |
Post-op |
+ |
-4 |
2 |
PD |
Increased |
Increased |
1.0
mg |
61 |
Man |
Pancreas |
Inoperable |
+ |
21 |
-1 |
SD |
Increased |
Increased |
1.0
mg |
84 |
Woman |
Colon |
Post-op |
+ |
28 |
14 |
SD |
Increased |
Increased |
1.0
mg |
69 |
Man |
Stomach |
Post-op |
+ |
7 |
26 |
SD |
Increased |
Increased |
1.0
mg |
59 |
Man |
Colon |
Post-op |
+ |
29 |
16 |
PD |
Increased |
Increased |
1.0
mg |
62 |
Man |
Colon |
Post-op |
+ |
15 |
2 |
PD |
Increased |
WNL |
3.0
mg |
41 |
Woman |
Pancreas |
Post-op |
+ |
12 |
158 |
SD |
WNL |
Stable |
3.0
mg |
66 |
Man |
Pancreas |
Inoperable |
+ |
12 |
19 |
SD |
Decreased |
Increased |
3.0
mg |
64 |
Man |
Pancreas |
Post-op |
+ |
2 |
-16 |
SD |
WNL |
Decreased |
3.0
mg |
50 |
Man |
Pancreas |
Post-op |
+ |
12 |
21 |
PD |
WNL |
Increased |
3.0
mg |
64 |
Woman |
Pancreas |
Inoperable |
+ |
0 |
10 |
PD |
Increased |
Increased |
Post-op: Post-Operative, SD: Stable Disease, PD: Progressive Disease, WNL:
Within the Normal Limit