Table 3: Univariable analysis of factors associated with all-cause reintubation. Data are expressed as mean ± SD, median (interquartile range), or number and percentage (%).

 

Failed   extubation

n = 26

Successful extubation

n = 196

P

At least one high risk factor for reintubation

18 (69.2%)

114 (58.2%)

0.28

Heart disease

10 (38.4%)

35 (17.8%)

< 0.01

APACHE II > 12 at extubation

20 (76.9%)

83 (42.3%)

< 0.01

Length of mechanical ventilation > 10 days before extubation

20 (76.9%)

88 (44.9%)

< 0.01

Hypercapnia after extubation

11 (42.3%)

4 (2.1%)

< 0.01

Laryngeal edema after extubation

3 (11.5%)

1 (0.5%)

<  0.01

FiO2 > 35% at 12-h after extubation

24 (92.3%)

88 (44.9%)

< 0.01

Gas-flow (only HFO), L/min

34 ± 3.9

40 ± 2.5

0.09

Gas-flow (only HFO) > 35 L/min at 12-h after extubation

9 (34.6%)

0 (0%)

0.01

 

APACHE = acute physiology and chronic health evaluation; HFO = high flow oxygen therapy; ICU = intensive care unit.