Table 1: Baseline characteristics and clinical data of the study population according to the intracoronary nitrate administration before PCI.
Parameters |
PCI with nitrate (212) |
PCI without nitrate (100) |
P value |
Age (years) |
61 ± 11 |
63 ± 12 |
NS |
BMI (kg/m2) |
30.1 ± 6.0 |
29.5 ± 5.5 |
NS |
Waist circumference (cm) |
106 ± 14 |
101 ± 13 |
0.003 |
Gender (male) (%) |
84 |
82 |
NS |
Hypertension (%) |
48 |
61 |
0.033 |
Diabetes mellitus (%) |
33 |
36 |
NS |
Smoking status (%) |
48.1 |
54 |
NS |
Hyperlipidemia (%) |
31 |
36 |
NS |
Family history of CAD (%) |
41 |
34 |
NS |
PAD (%) |
1 |
3 |
NS |
Systolic blood pressure (mmHg) |
130 ± 22 |
129 ± 17 |
NS |
Diastolic blood pressure (mmHg) |
78 ± 13 |
77 ± 11 |
NS |
Plasma blood glucose (mg/dl) |
158 ± 75 |
146 ± 71 |
NS |
Uric acid (mg/dl) |
5.79 ± 1.55 |
6.30 ± 1.93 |
0.014 |
Creatinine (mg/dl) |
0.97 ± 0.3 |
1.05 ± 0.4 |
0.039 |
Total cholesterol (mg/dl) |
198 ± 43 |
190 ± 46 |
NS |
LDL (mg/dl) |
130 ± 39 |
121 ± 38 |
NS |
HDL (mg/dl) |
39 ± 8 |
40 ± 10 |
NS |
Triglyceride (mg/dl) |
152 ± 110 |
153 ± 101 |
NS |
Leukocytes (103/mm3) |
10.6 ± 3.5 |
10.1 ± 3.1 |
NS |
CRP (mg/dl) |
0.98 ± 1.41 |
1.68 ± 3.92 |
NS |
Hemoglobin (mg/dl) |
14.2 ± 1.7 |
14.3 ± 2.0 |
NS |
AST (U/L) |
45 ± 46 |
38 ± 36 |
NS |
ALT (U/L) |
26 ± 16 |
25 ± 20 |
NS |
GGT (U/L) |
29 ± 17 |
31 ± 19 |
NS |
LDH (U/L) |
337 ± 152 |
356 ± 205 |
NS |
Total bilirubin (mg/dL) |
0.62 ± 0.30 |
0.79 ± 0.55 |
0.007 |
Direk bilirubin (mg/dL) |
0.19 ± 0.10 |
0.26 ± 0.19 |
0.005 |
Aortic sclerosis (%) |
49.5 |
60 |
NS |
Medications |
|
|
|
ASA (%) |
20.3 |
34.0 |
0.009 |
BB (%) |
19.8 |
29 |
NS |
CCB (%) |
12.3 |
14 |
NS |
Oral nitrate (%) |
0.9 |
1 |
NS |
ACEi (%) |
12.7 |
24 |
0.012 |
Statin (%) |
9.4 |
21 |
0.005 |
PPI (%) |
13.7 |
13 |
NS |
Clopidogrel (%) |
5.2 |
6 |
NS |
BMI: Body Mass Index; CAD: Coronary Artery Disease; PAD: Peripheral Arterial Disease, LDL: Low Density Lipoprotein; HDL: High Density Lipoprotein; CRP: C-Reactive Protein; AST: Aspartate Transaminase; ALT: Alanine Aminotransferase; GGT: Gama-Glutamyl Transferase; LDH: Lactate Dehydrogenase; ASA: Acetylsalicylic Acid; BB: Beta Blocker; Acei: Angiotensinogen Converting Enzyme Inhibitor; PPI: Proton Pump Inhibitor