Association between serum 25-OH vitamin D and cardiovascular risk factors in patients with chronic kidney disease.

Table 3: Association between serum 25-OH vitamin D and cardiovascular risk factors in patients with chronic kidney disease.

Cardiovascular risk factors	Serum 25-0H vitamin D		p-value
Cardiovascular risk factors	Normal (n = 28)	Insufficient/deficient (n = 109)
Demographic
Age	59.1 ± 16.2	57.5 ± 15.3	0.633
Gender
Male	17 (60.7%)	45 (41.3%)	0.065
Female	11 (39.3%)	64 (58.7%)
Race
Non-black	22 (78.6%)	89 (81.6%)	0.711
Black	6 (21.4%)	20 (18.4%)
Cardiovascular risk factors
BMI^a	25.5 ± 4.7	27.4 ± 5.5	0.092
Obesity	2 (7.1%)	27 (26.0%)	0.033^*
Inactivity	19 (70.4%)	85 (80.2%)	0.270
Hypertension	25 (89.3%)	97 (89.0%)	0.964
DM	6 (21.4%)	42 (38.9%)	0.085
CAD	3 (11.1%)	17 (15.6%)	0.556
History of stroke	7 (25.9%)	14 (13.0%)	0.096
Dyslipidemia	15 (53.6%)	70 (64.2%)	0.300
Laboratory findings
Hemoglobin ^{a b}	12.77 ± 1.88	11.45 ± 1,68	0.004^*
Cholesterol^{a c}	157 (125; 176)	174 (151; 206)	0.028^*
PTH^a	176 (107; 277)	261 (160; 382)	0.060
Calcium^a	9.43 ± 0.57	9.09 ± 0.65	0.015^*
Phosphorus	3.79 ± 1.45	4.10 ± 1.20	0.324
Albumin^c	4.05 ± 0.46	3.93 ± 0.52	0.391
AP	75 (55; 97)	90 (69; 117)	0.203
Creatinine	2.21 (1.9; 3.1)	2.50 (1.9; 3.8)	0.434
GFR	26,6 ± 8,9	25,0 ± 11,8	0,501

^*Statistically significant association (p < 0.05); ^aStatistically significant difference between the normal and deficient groups (p < 0.05); ^bStatistically significant difference between the normal and insufficient groups (p < 0.05); ^cStatistically significant difference between the insufficient and deficient groups (p < 0.05).

Abbreviations: BMI: Body mass index; CAD: Coronary artery disease; ADPKD: Autosomal dominant polycystic kidney disease; CPN: Chronic pyelonephritis; Vit D: 25-OH vitamin D; PTH: Parathyroid hormone; AP: Alkaline phosphatase; GFR: glomerular filtration rate.