Table 1: Effects of Energy Drink Ingredient of Endothelial Function.
Ingredient | Effect on Endothelial Function | Therapy | Comments |
L-Carnitine | Increase | *PAD | Further long term studies needed & which isomer would be most effective |
Guarana | NF | NR | - |
Inositol | NF | NR | - |
Glucuronolactone | NF | NR | - |
Taurine | Increase | *DM1 | Further elucidation for mechanism of action in DM1 patients and protective effects in pro-inflammatory states |
Ginseng | Increase / no effect | *DM2/HTN | Delineation between KRG and ARG to determine which has greater potential for therapy; also what are the active compounds in the marketed preparations |
Glucose | Decrease | NR | All advocated a decrease in serum levels of glucose being beneficial to patients |
Caffeine | Decrease | NR | Possible use in coronary artery disease since a study showed improvement after purified caffeine pills |
Riboflavin | NF | NR | - |
Niacin | Increase / no effect | CAD/DM2/MS/HLD | Clarification on beginning treatment on statin therapy and at what levels of high-density lipoprotein cholesterol |
Pyridoxine | Increase / no effect | *HHC/CAD | Studies on healthy, without folate, and long-term studies with HHC |
Cyanocobalamin | No effect | *HHC/MS | Studies without folate and role in HHC therapy |
NF: No articles Found; NR: No Recommendations at this time; *: Possible role in therapy; PAD: Peripheral Arterial Disease; HTN: Hypertension; DM: Diabetes Mellitus; HLD: Hyperlipidemia; HHC: Hyperhomocysteinemia |