Table 3: Comparison of HbF concentration and markers of Liver function in steady state and crises state subjects in SCD.

Table 3: Comparison of HbF concentration and markers of Liver function in steady state and crises state subjects in SCD.

Biochemical Markers

Steady State (N = 20)

Crises State (N = 10)

P-Value

HbF (%)

Bilirubin. (µmol/L)

ALT

AST

AST/ALT

2.15 ± 1.44

30.95 ± 18.82

22.89 ± 11.20

61.07 ± 11.12

3.08 ± 1.07

1.62 ± 1.16

36.44 ± 27.09

26.36 ± 15.05

65.41 ± 14.51

2.90 ± 1.11

0.401

0.599

0.554

0.555

0.738

HbF: Foetal Haemoglobin; TB: Total Bilirubin; ALT: Alanine Transaminase; AST: Aspartate Transaminase; AST/ALT: De-ritis ratio