Table 1: A comparison of the HbF Concentration and liver function markers between subjects with SCD and apparently healthy control subjects.

Biochemical Markers

SCD (35)

(Mean ± SD)

Control (15)

(Mean ± SD)

P-value

TB (µmol/L)

ALT

AST

HbF (%)

35.52 ± 25.70

23.47 ± 11.69

61.80 ± 11.58

2.06 ± 1.39

18.68 ± 3.76

13.27 ± 5.04

28.17 ± 16.18

1.42 ± 0.84

0.001*

0.020*

0.001*

0.018*

HbF: Foetal Haemoglobin; TB: Total Bilirubin; ALT: Alanine Transaminase; AST: Aspartate Transaminase

*Correlation is significant at 0.05 (P < 0.05).