Features

Very good cytogenetics subgroup (n = 2)

Good cytogenetics subgroup (n = 68)

Intermediate cytogenetics subgroup (n = 40)

Poor cytogenetics subgroup (n = 17)

Very poor cytogenetics subgroup (n = 26)

Median age at diagnosis (years)

41

67

71

67

66

Male:Female ratio

2:00

1.5:1

1.2:1

1.4:1

1.2:1

Median time of follow-up (days)

479

534

564

662

445

Transplant history (with/without)

100% (2/2)

34% (23/68)

25% (10/40)

65% (11/17)

50% (13/26)

Mutation at initial diagnosis (with/total)

0% (0/2)

85% (58/68)

93% (37/40)

76% (13/17)

92% (24/26)

Evolved to overt AML (with/total)

0% (0/2)

16% (11/68)

23% (9/40)

12% (2/17)

23% (6/26)

Presence of germline mutations

0% (0/2)

4% (3/68)

8% (3/40)

6% (1/17)

0% (0/26)