Prognostic subgroup

Defining cytogenetic abnormalities

Very good

Loss of Y chromosome

del(11q)

Good

Normal

del(5q)

del(12p)

del(20q)

Double, including del(5q)

Intermediate

del(7q)

Gain of chromosome 8

Gain of chromosome 19

Isochromosome 17q

Single or double abnormalities not specified in other subgroups

Two or more independent non-complex clones

Poor

Loss of chromosome 7

inv(3), t(3q) or del(3q)

Double including loss of chromosome 7 or del(7q)

Complex (3 Abnormalities)

Very poor

Complex (> 3 Abnormalities)