Table 1: Demographic data of Alloimmunized vs. Not-alloimmunized.

Demographic data Alloimmunized (n = 8) Not-Alloimmunized (n = 64) P value
Age (years old) 12.25 (± 2.5) 11.48 (± 2.8) 0.460*
Gender 0.675***
Male 5 (62.5%) 35 (54.7%)
Female 3 (37.5%) 29 (47.3%)
Diagnose 0.095***
SCA 8 (100%) 47 (73.4%)
SCD 0 17 (26.6%)
Type of Blood Component 0.464**
RBC (NON Phenotyped leukoreduced) 4 (50%) 38 (59.3%)
Phenotyped leukoreduced RBC 2 (25%) 7 (11%)
RBC and Phenotyped leukoreduced RBC 2 (25%) 19 (29.7%)
Total number of transfusions
Total 19.25 (± 21.9) 11.8 (± 20.2) 0.085**
Total number of transfusions within Age groups
0-4 years-old 5.0 (± 7.8) 2.2 (± 4.0) 0.420**
5-10 years-old 11.6 (± 12.7) 6.3 (± 10.8) 0.064**
Over 10-years-old 2.6 (± 5.9) 3.3 (± 13.2) 0.825**
Total number of transfusions 0.063***
≤ 10 transfusions 3 (6.3%) 45 (93.8%)
> 10 transfusions 5 (20.8%) 19 (79.2%)
RBC units transfused previous positive IAT - Antibody screening 8.0 (± 12.9) -
Chronic Transfusion Therapy 2 (22.2%) 7 (77.8%) 0.257*

*Student's T-test **Mann-Whitney's U test and ***Pearson's Chi Square Test