Table 1: Demographic data of Alloimmunized vs. Not-alloimmunized.
Demographic data | Alloimmunized (n = 8) | Not-Alloimmunized (n = 64) | P value |
Age (years old) | 12.25 (± 2.5) | 11.48 (± 2.8) | 0.460* |
Gender | 0.675*** | ||
Male | 5 (62.5%) | 35 (54.7%) | |
Female | 3 (37.5%) | 29 (47.3%) | |
Diagnose | 0.095*** | ||
SCA | 8 (100%) | 47 (73.4%) | |
SCD | 0 | 17 (26.6%) | |
Type of Blood Component | 0.464** | ||
RBC (NON Phenotyped leukoreduced) | 4 (50%) | 38 (59.3%) | |
Phenotyped leukoreduced RBC | 2 (25%) | 7 (11%) | |
RBC and Phenotyped leukoreduced RBC | 2 (25%) | 19 (29.7%) | |
Total number of transfusions | |||
Total | 19.25 (± 21.9) | 11.8 (± 20.2) | 0.085** |
Total number of transfusions within Age groups | |||
0-4 years-old | 5.0 (± 7.8) | 2.2 (± 4.0) | 0.420** |
5-10 years-old | 11.6 (± 12.7) | 6.3 (± 10.8) | 0.064** |
Over 10-years-old | 2.6 (± 5.9) | 3.3 (± 13.2) | 0.825** |
Total number of transfusions | 0.063*** | ||
≤ 10 transfusions | 3 (6.3%) | 45 (93.8%) | |
> 10 transfusions | 5 (20.8%) | 19 (79.2%) | |
RBC units transfused previous positive IAT - Antibody screening | 8.0 (± 12.9) | - | |
Chronic Transfusion Therapy | 2 (22.2%) | 7 (77.8%) | 0.257* |
*Student's T-test **Mann-Whitney's U test and ***Pearson's Chi Square Test