Analysis of factors prone to influence two different types of treatment response ( ≥ 2 g/dl vs. ≥ 3 g/dl increase in hemoglobin levels).

Table 4: Analysis of factors prone to influence two different types of treatment response ( ≥ 2 g/dl vs. ≥ 3 g/dl increase in hemoglobin levels).

	Hemoglobin difference > 2		Hemoglobin difference > 3
	OR (95% CI)	p-value	OR (95% CI)	p-value
Age	0.98 (0.96, 1.00)	0.094	1.00 (0.98, 1.02)	0.772
Male gender	1.29 (0.66, 2.51)	0.463	1.82 (0.89, 3.72)	0.101
Total dose	1.95 (1.1, 3.46)	0.022^*	1.24 (0.74, 2.08)	0.410
Etiology^a
Pregnancy	-	-
GIS	0.28 (0.03, 3.06)	0.297	1.27 (0.29, 5.57)	0.748
GUS	0.24 (0.02, 2.8)	0.257	1.81 (0.38, 8.53)	0.453
Malignancy	0.74 (0.06, 10.04)	0.823	2.36 (0.43, 12.91)	0.323
Nutritional	0.51 (0.03, 8.06)	0.629	3.61 (0.56, 23.22)	0.177
Other	0.27 (0.02, 3.04)	0.290	3.13 (0.68, 14.41)	0.143
Chronic renal failure	0.84 (0.39, 1.81)	0.656	0.53 (0.24, 1.19)	0.126
Bariatric surgery	0.66 (0.20, 2.13)	0.483	0.27 (0.08, 0.88)	0.030^*
Pre-treatment Hb (g/dl)	0.17 (0.08, 0.35)	< 0.001^*	0.22 (0.12, 0.44)	< 0.001^*
Pre-treatment Hct (%)	1.46 (1.17, 1.83)	0.001^*	1.43 (1.16, 1.76)	0.001^*
Pre-treatment MCV (fl)	0.99 (0.95, 1.03)	0.616	0.93 (0.90, 0.97)	0.001^*
Pre-treatment ferritin (ng/mL)	0.89 (0.84, 0.94)	< 0.001^*	0.93 (0.87, 0.98)	0.008^*
Pre-treatment TS (%)	1.01 (0.93, 1.09)	0.861	1 (0.93, 1.08)	0.965

(Hint: CI: confidence interval, OR: Odds ratio, ^aReference group: pregnancy); (GIS: gastrointestinal system; GUS: genitourinary system; Hb: hemoglobin; Hct: hematocrit; MCV: mean corpuscular volume; TS: transferrin saturation).