Table 2:Demographic characteristics of the study population.

Platelet aggregation

ADP

EPI

Reagent concentration (uM)

0.58

1.17

2.34

0.55

1.1

11

Normal range (% aggregation)

3-10

11-23

20-60

8-15

10-30

20-90

Diagnostic criteria

Suggestive diagnosis

History of TE and hyperaggregability at a concentration of a reagent

Confirmed diagnosis

History of ET and hyperaggregability at two concentrations of two reagents

 

History of ET and hyperaggregability at a concentration of two reagents

 

History of TE and repeated hyperaggregability confirmed at one reagent concentration

Laboratory classification

Type I: Hyperaggregability to ADP and EPI

Type 2: Hyperaggregability only to EPI

Type 3: Hyperaggregability to ADP only

ADP: Adenosine Diphosphate; EPI: Epinephrine; TE: Thromboembolism (table adapted from Mammen)