Table 2: Classification of thrombocytopenia's etiology according to the trimester PLT count. Others include: Bone marrow failure, antiphospholipid antibody syndrome, autoimmune conditions.

Etiology of thrombocytopenia according to the trimester and PLT count

First Trimester

Second Trimester

Third Trimester

Immune thrombocytopenia (ITP)

PLT > 100,000 μL

PLT > 100,000 μL

Hereditary thrombocytopenia (HT)

Gestational thrombocytopenia

Gestational thrombocytopenia

Others

ITP

Pre-eclampia/HELLP

Thrombotic microangiopathy (TMA)

Pre-eclampia/HELLP

Others/TMA/ITP/HT

 

HT/Others/TMA

 

 

PLT < 100,000 μL

PLT < 50,000 μL

 

ITP

Pre-eclampia/HELLP

 

HT

ITP

 

Pre-eclampia/HELLP

Others

 

Others

TMA

 

Gestational thrombocytopenia

Gestational thrombocytopenia/HT

 

TMA