Synthesis of our results, showing only those with statistically significant values. Four comparative studies showed higher level of TLRs and inflammatory mediators in blood samples obtained from patients who received only propofol or mixed anaesthesia with propofol and sevoflurane. The only exception was IL8 at 72 hours and at 7 days after surgery when compared sevoflurane only versus mixed anaesthesia. IL8 was higher in sevoflurane anaesthesia group.

Table 2: Synthesis of our results, showing only those with statistically significant values.

Four comparative studies showed higher level of TLRs and inflammatory mediators in blood samples obtained from patients who received only propofol or mixed anaesthesia with propofol and sevoflurane. The only exception was IL8 at 72 hours and at 7 days after surgery when compared sevoflurane only versus mixed anaesthesia. IL8 was higher in sevoflurane anaesthesia group.

Statistically signification achieved (p < 0.05)
Univariant study	♦	●	■	⨀
TLR2 monocytes immediately after surgery	+	-	+	-
TLR2 monocytes 24 hours	+	-	+	-
TLR2 monocytes 72 hours	+	+	+	-
IL-6 24 hours	+	-	+	-
IL-6 day 7 after surgery	+	-	-	-
TNFα immediately after surgery	+	+	+	-
proBNP day 7 after surgery	+	+	-	+
IL-2R day 7 after surgery	+	+	-	-
IL-8 72 hours after surgery	-	-	+ (> In sevoflurane)	+
IL-8 day 7 after surgery	-	-	+ (> In sevoflurane)	-

♦Sevoflurane versus propofol during the whole anaesthetic time (including CBP); ●Sevoflurane versus propofol for maintenance period (before and after CBP); ■Sevoflurane only versus mixed anaesthesia (propofol-sevoflurane); ⨀Propofol only versus mixed anaesthesia (propofol-sevoflurane).