Table 2: EPOC Tool for assessment of methodical quality of Non-RCTS.

Outcome Patel 2016 Marra 2013 Chen 2011 Allegranzi 2010 Rosenthal 2005
Was allocation adequately concealed No No No No
Were baseline outcome measurements similar? Yes Yes Yes Yes Yes
Were baseline characteristics similar? Yes Yes Yes Yes Yes
Did the study report incomplete data? Yes Yes Yes Yes Yes
Did study distinctly describe intervention across the groups? Yes Yes Yes Yes Yes
Did study prevent knowledge of intervention during the process? No Yes No Yes Yes
Was the study adequately protected against contamination? No Yes Yes Yes Yes
Did study prevent reporting of selective outcome Yes Yes Yes Yes Yes
Was the study free from other biases? Yes Yes Yes Yes Yes
Total score 6/9 8/9 7/9 8/9 8/9