Table S2: Regression slopes with p-values by age and gender for the models fitted for log10 transformed values of thyroid stimulating hormone (TSH in nIU/mL), free triiodothyronine (FT3 in fg/mL), free thyroxin (FT4 in pg/dL), total triiodothyronine (TT3 in pg/dL), total thyroxin (TT4 in ng/mL), and thyroglobulin (TGN in fg/mL) when association with urine lead was investigated. Data from National Health and Nutrition Examination Survey 2007-2012.
| Gender: IOS | Independent variable | TSH | FT3 | FT4 | TT3 | TT4 | TGN |
|---|---|---|---|---|---|---|---|
| Male: IOD* | Use other drugs | -0.041729571 (0.23) | -0.004998617 (0.28) | 0.0058692827 (0.57) | -0.008826299 (0.35) | 0.0127114681 (0.25) | -0.012511563 (0.78) |
| Fasting in hours | 0.001053229 (0.59) | 0.0013697767 (0) | 0.0005277099 (0.22) | 0.0014467365 (0.07) | 0.0004071162 (0.54) | 0.0004843149 (0.9) | |
| Poverty income ratio | 0.0029208698 (0.68) | -0.002606113 (0.05) | -0.000306579 (0.88) | -0.003209813 (0.18) | -0.00151061 (0.36) | -0.003193748 (0.79) | |
| Log10 of Body Mass Index | 0.1291103684 (0.4) | 0.0149201116 (0.53) | 0.0307936898 (0.45) | 0.0792441774 (0.13) | 0.092007564 (0.07) | 0.0031531602 (0.99) | |
| Log10 of Serum Albumin | 0.4129115234 (0.32) | 0.1883106832 (0.01) | -0.109531337 (0.28) | 0.3333803522 (0.01) | -0.08160535 (0.39) | -0.794363062 (0.14) | |
| Lg10 of Urine Lead | 0.0953369519 (0.11) | 0.001840619 (0.72) | -0.023835145 (0.02) | 0.0025197556 (0.81) | -0.008671475 (0.35) | 0.0153603499 (0.78) | |
| NHANES survey cycle | 0.00778842 (0.71) | -0.004064014 (0.19) | 0.013635186 (0) | -0.002955405 (0.56) | -0.00896487 (0.06) | 0.0133139461 (0.5) | |
| Log10 of Urine Creatinine | -0.086948445 (0.16) | 0.0160065483 (0.07) | 0.0174653237 (0.14) | 0.0164875274 (0.22) | 0.0080016924 (0.49) | 0.1291737626 (0.08) | |
| R2 in percent | 2.2 | 30.6 | 7.0 | 17.2 | 5.1 | 10.5 | |
| Male: IOR* | Use other drugs | 0.0158209176 (0.58) | -0.015118854 (0) | 0.005516323 (0.43) | -0.021867024 (0) | 0.0091927245 (0.35) | -0.060404399 (0.08) |
| Fasting in hours | 0.0002345584 (0.87) | 0.0009736951 (0) | 0.0005191691 (0.2) | 0.0013028445 (0.01) | 0.0008275148 (0.01) | -0.002903823 (0.2) | |
| Poverty income ratio | -0.004671608 (0.39) | -0.003101883 (0.01) | -0.000113954 (0.94) | -0.005812839 (0) | -0.00054396 (0.74) | -0.001325143 (0.86) | |
| Log10 of Body Mass Index | 0.2604719205 (0.03) | 0.0457424671 (0.01) | -0.093562406 (0) | 0.1095715878 (0) | 0.0889042563 (0) | 0.3685867642 (0) | |
| Log10 of Serum Albumin | 0.4786779581 (0.06) | 0.2440321318 (0) | -0.128463955 (0.07) | 0.3102244212 (0.01) | -0.043956356 (0.65) | -0.67335109 (0.12) | |
| Lg10 of Urine Lead | 0.0410074728 (0.1) | -0.004712712 (0.33) | -0.024040038 (0.01) | 0.0039154333 (0.56) | -0.015953964 (0.05) | 0.0517085591 (0.16) | |
| NHANES survey cycle | -0.001768468 (0.87) | -0.003666564 (0.19) | 0.0085708044 (0.05) | 0.0002098628 (0.96) | -0.011986282 (0) | 0.0012280675 (0.93) | |
| Log10 of Urine Creatinine | -0.044428942 (0.4) | 0.0146126729 (0.06) | 0.0183813787 (0.13) | 0.0075758394 (0.46) | 0.0064332484 (0.7) | -0.087538719 (0.16) | |
| R2 in percent | 6.1 | 30.8 | 6.1 | 20.5 | 5.7 | 6.0 | |
| Female: IOD* | Use other drugs | -0.030970781 (0.3) | -0.005814891 (0.36) | 0.0092684511 (0.32) | -0.009887018 (0.46) | 0.0177998781 (0.1) | 0.0441167345 (0.4) |
| Fasting in hours | 0.0093415716 (0.01) | 0.000975207 (0.01) | 0.0002025127 (0.72) | 0.0001525891 (0.83) | 0.0003948886 (0.54) | -0.000721781 (0.76) | |
| Poverty income ratio | -0.002437874 (0.75) | -0.002929346 (0.09) | -0.001634487 (0.43) | -0.004732598 (0.03) | -0.004180829 (0.03) | -0.011892319 (0.17) | |
| Log10 of Body Mass Index | 0.1432673728 (0.28) | 0.0745862222 (0) | -0.006438141 (0.86) | 0.1046194589 (0.03) | 0.1279341042 (0) | -0.103299472 (0.58) | |
| Log10 of Serum Albumin | -0.275062447 (0.35) | 0.2467554083 (0) | 0.0397201057 (0.68) | -0.018621729 (0.88) | -0.273818575 (0.01) | -0.242771295 (0.65) | |
| Lg10 of Urine Lead | 0.0001457806 (1) | -0.023101706 (0.01) | 0.0107963267 (0.36) | -0.02725571 (0.02) | -0.009828297 (0.42) | 0.023556915 (0.7) | |
| NHANES survey cycle | 0.0013230706 (0.94) | -0.002343581 (0.25) | 0.0157923713 (0) | 0.0006743429 (0.85) | -0.008096723 (0.09) | -0.004495262 (0.82) | |
| Premenarche | 0.1949854466 (0.01) | 0.0396472053 (0.01) | -0.017500274 (0.32) | 0.1023391137 (0) | -0.03661465 (0.03) | 0.1073157638 (0.35) | |
| Menopause | 0.0589830325 (0.16) | -0.004784154 (0.43) | 0.0084306603 (0.41) | 0.0022860747 (0.86) | 0.0021618108 (0.85) | 0.0886920045 (0.09) | |
| No of live births | -0.008815085 (0.29) | 0.0000857385 (0.95) | -0.001533925 (0.38) | 0.0002667178 (0.92) | 0.0017312153 (0.42) | -0.012177621 (0.33) | |
| Log10 of Urine Creatinine | -0.012920841 (0.78) | 0.0219270083 (0.01) | -0.006418433 (0.67) | 0.0289782561 (0.04) | -0.000072435 (1) | -0.05737875 (0.37) | |
| R2 in percent | 9.5 | 20.0 | 6.0 | 8.6 | 12.4 | 8.8 | |
| Female: IOR* | Use other drugs | -0.000835102 (0.97) | -0.018293566 (0) | 0.0001061241 (0.99) | -0.035970654 (0) | -0.003528111 (0.67) | 0.0247968783 (0.5) |
| Fasting in hours | 0.0049804044 (0.01) | 0.0012219425 (0) | 0.000563582 (0.26) | 0.00132801 (0.02) | 0.0002487644 (0.67) | 0.0019567428 (0.46) | |
| Poverty income ratio | 0.0013969862 (0.8) | -0.003622742 (0) | 0.0012522923 (0.44) | -0.006915019 (0.01) | -0.000863236 (0.61) | -0.002982205 (0.75) | |
| Log10 of Body Mass Index | 0.3711518293 (0) | 0.0591197244 (0) | -0.045367546 (0.02) | 0.0777061983 (0) | 0.0530403314 (0.02) | 0.1063789949 (0.44) | |
| Log10 of Serum Albumin | 0.1484132393 (0.66) | 0.2109729765 (0) | -0.092892315 (0.21) | 0.020716145 (0.87) | -0.370987992 (0) | -0.229754537 (0.55) | |
| Lg10 of Urine Lead | -0.022938005 (0.59) | -0.007028532 (0.27) | 0.0011231727 (0.88) | -0.021506431 (0.04) | -0.017114036 (0.16) | -0.038422486 (0.56) | |
| NHANES survey cycle | 0.0042268246 (0.69) | -0.001479838 (0.58) | 0.0140811206 (0) | 0.0050989341 (0.34) | -0.006420846 (0.18) | -0.00008967 (1) | |
| Premenarche | 0.2041473346 (0.02) | 0.0460675003 (0) | -0.012450181 (0.52) | 0.0492137682 (0.01) | -0.03785661 (0.08) | 0.0268229674 (0.87) | |
| Menopause | 0.0466849563 (0.12) | 0.0011550495 (0.81) | 0.0072606064 (0.29) | 0.0058881765 (0.52) | 0.0034871102 (0.68) | 0.0381946363 (0.4) | |
| No of live births | -0.003275855 (0.53) | -0.002910525 (0.01) | -0.000984332 (0.42) | -0.002921732 (0.06) | -0.000265694 (0.88) | 0.0133847812 (0.2) | |
| Log10 of Urine Creatinine | -0.078257244 (0.09) | 0.0256713699 (0.01) | 0.0044048337 (0.7) | 0.0267121505 (0.13) | 0.0074417583 (0.67) | 0.0430685262 (0.63) | |
| R2 in percent | 10.2 | 23.3 | 7.6 | 13.7 | 6.5 | 7.1 |
*IOD = Iodine Deficient or urine iodine < 100 ng/mL; IOR = Iodine Replete or urine iodine ≥ 100 ng/mL.